Miller , Jacques Francis Albert Pierre

Miller , Jacques Francis Albert Pierre
(1931–) French–Australian immunologist
Miller, who was born at Nice in the south of France, was educated at the University of Sydney, Australia, and at University College, London, where he obtained his PhD in 1960. He then held brief appointments at the Chester Beatty Research Institute in London and the National Cancer Institute in Bethesda, Maryland. Miller returned to Australia in 1966 to serve as head of the experimental pathology department at the Hall Institute of Medical Research, Melbourne.
In 1961 Miller succeeded in solving an ancient medical mystery. The thymus gland is a large organ placed in the chest beneath the breastbone. Surprisingly, until 1961 scientists lacked any clear idea of the role played by such a prominent body. The normal technique in such a situation is to watch for any changes in the behavior of the subject when the organ has been removed. In this case thymectomy seemed to make no discernible difference to the behavior of any experimental animal.
Working within this tradition Miller performed a surgical operation of great skill, the removal of the thymus from one-day-old mice. As the mice weigh no more than a gram and are no bigger than an inch it is not difficult to see why such an operation had been little attempted before. In this case, however, the excision did lead to dramatic and obvious changes. The mice failed to develop properly and usually died within two to three months of the operation. Just what was wrong with them became clear when Miller went on to test their ability to reject skin grafts, a sure sign of a healthy immune system. Miller's mice could tolerate grafts from unrelated mice and sometimes even from rats. This made it quite clear that the thymus was deeply involved in the body's immune system but just what precise role it played was to occupy immunologists for a decade or more.
Much of Miller's work was performed independently, also in 1961, by a team under the direction of Robert Good at Minnesota.

Scientists. . 2011.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Jacques Miller — Para el psicoanalista francés, véase Jacques Alain Miller. Jacques Francis Albert Pierre Miller Nacimiento 2 de abril de 1931 Niza Alma máter Universidad de Sídney Conocido&# …   Wikipedia Español

  • Jacques Miller — Jacques Francis Albert Pierre Miller AC FRS (né le 2 avril 1931 à Nice, France) est un scientifique australien. Il est célèbre pour avoir découvert la fonction immunologique du thymus[1] et pour avoir identifié chez les mammifères les deux… …   Wikipédia en Français

  • Jacques Miller — Jacques Francis Albert Pierre Miller (* 2. April 1931 in Nizza) ist ein australischer Wissenschaftler französischer Herkunft, der als Entdecker der T Zell Immunologie gilt. Miller wuchs in Frankreich, in der Schweiz und in China auf. Nach dem… …   Deutsch Wikipedia

  • Jacques Miller — Infobox Scientist name = Jacques Francis Albert Pierre Miller box width = image width =150px caption = Jacques Francis Albert Pierre Miller birth date = April 2 1931 birth place = Nice death date = death place = residence = citizenship =… …   Wikipedia

  • Miller — /ˈmɪlə/ (say miluh) noun 1. Alex, born 1936, Australian writer; work includes the novels The Ancestor Game (1992) and Journey to the Stone Country (2002) both of which won the Miles Franklin Award (1993 and 2003). 2. Alexander, 1842–1914,… …  

  • Pierre Cuq — Pierre Mondy Pierre Mondy Nom de naissance Pierre Cuq Naissance 10 février 1925 (84 ans) Neuilly sur Seine, France Nationalité(s) Française …   Wikipédia en Français

  • Pierre Mondy — Données clés Nom de naissance Pierre Cuq Naissance 10 février 1925 (1925 02 10) (86 ans) Neuilly sur Seine, France Nationalité Française …   Wikipédia en Français

  • Jacques Mauclair — Données clés Naissance 12 janvier 1919 Paris, France Nationalité  France Décès 20  …   Wikipédia en Français

  • Francis Perrin (comédien) — Francis Perrin (acteur) Pour les articles homonymes, voir Francis Perrin et Perrin. Francis Perrin Naissance 10 octobre 1947 (61 ans) Versailles, France N …   Wikipédia en Français

  • Jacques Leguerney — (1906 1997) was a French composer especially noted for his art songs.BiographyJacques Leguerney has been referred to as the latest perhaps the last great exponent of the mélodie . [Richard Miller, CHOICE (publication of the Association of College …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”