Holley , Robert William

Holley , Robert William
(1922–1993) American biochemist
Holley was born in Urbana, Illinois. After graduating in chemistry from Illinois University in 1942, he joined the team at Cornell Medical School that achieved the first artificial synthesis of penicillin. He remained at Cornell to receive his PhD in organic chemistry in 1947.
Two years (1955–56) spent at the California Institute of Technology marked the beginning of Holley's important research on the nucleic acids. He decided that to work out the structure of a nucleic acid he first needed a very pure specimen of the molecule. Back again at Cornell, his research team spent three years isolating one gram of alanine transfer RNA (alanine tRNA) from some 90 kilograms of yeast. In March 1965 he was able to announce that they had worked out the complete sequence of 77 nucleotides in alanine tRNA. For this work Holley received the 1968 Nobel Prize for physiology or medicine, an award he shared with Marshall Nirenberg and Har Gobind Khorana.

Scientists. . 2011.

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  • Holley,Robert William — Hol·ley (hŏlʹē), Robert William. 1922 1993. American biochemist. He shared a 1968 Nobel Prize for the study of genetic codes. * * * …   Universalium

  • Holley, Robert William — born Jan. 28, 1922, Urbana, Ill., U.S. died Feb. 11, 1993, Los Gatos, Calif. U.S. biochemist. He received his Ph.D. from Cornell University. Holley and others showed that transfer RNA was involved in the assembly of amino acids into proteins. He… …   Universalium

  • Holley, Robert William — (28 ene. 1922, Urbana, Ill., EE.UU.–11 feb. 1993, Los Gatos, Cal.). Bioquímico estadounidense. Obtuvo su Ph.D. en la Universidad Cornell. Holley y otros demostraron que el ARN de transferencia participaba en el ensamblado de aminoácidos para… …   Enciclopedia Universal

  • Robert William Holley — Robert W. Holley Robert W. Holley (links) Robert William Holley (* 28. Januar 1922 in Urbana, Illinois …   Deutsch Wikipedia

  • Medizinnobelpreis 1968: Robert William Holley — Har Gobind Khorana — Marshall Warren Nirenberg —   Die drei amerikanischen Wissenschaftler erhielten den Nobelpreis für »ihre Interpretation des genetischen Codes und dessen Funktion bei der Proteinsynthese«.    Biografien   Robert William Holley, * Urbana (Illinois) 28. 1. 1922, ✝ Los Gatos… …   Universal-Lexikon

  • Holley — Robert William …   Scientists

  • Robert Holley — Robert W. Holley Robert W. Holley (links) Robert William Holley (* 28. Januar 1922 in Urbana, Illinois …   Deutsch Wikipedia

  • Robert — /rob euhrt/, n. 1. Henry Martyn /mahr tn/, 1837 1923, U.S. engineer and authority on parliamentary procedure: author of Robert s Rules of Order (1876, revised 1915). 2. a male given name: from Germanic words meaning glory and bright. * * * (as… …   Universalium

  • William — /wil yeuhm/, n. 1. a word formerly used in communications to represent the letter W. 2. a male given name: from Germanic words meaning will and helmet. * * * (as used in expressions) Huddie William Ledbetter Aberhart William George William… …   Universalium

  • Robert — (as used in expressions) Adam, Robert Aldrich, Robert Altman, Robert (B.) Ashe, Arthur (Robert), Jr. Baden Powell (de Gilwell), Robert Stephenson Smyth, 1 barón Bakewell, Robert Baldwin, Robert Ballard Robert D(uane) Bly, Robert (Elwood) Borden,… …   Enciclopedia Universal